Tetrapyrroles and derivatives
Abcam Endothelin-1 (human, porcine), Vasoconstrictor peptide, 10UG
MW 2491.9 Da. Endothelin-1 (human, porcine), Vasoconstrictor peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam UCPH-101, Selective EAAT1 inhibitor, 1MG
MW 422.5 Da, Purity >98%. Selective inhibitor of EAAT1 (IC₅₀ = 0.67 μM). Displays >400-fold selectivity over EAAT2 and EAAT3. Blood-brain barrier permeable analog UCPH-102 also available (ab146404).
The product is subject to the following: Abcam Restricted Use Statement
Abcam CHIR99021, GSK3 inhibitor, 5MG
MW 465.3 Da, Purity >98%. Potent, highly selective aminopyrimidine GSK3 inhibitor (IC₅₀ values are 6.7 and 10 nM at GSK3β and GSK3α, respectively). Exhibits >500-fold selectivity for GSK3 against 20 closely related protein kinases and >800-fold selectivity for 23 additional enzymes and 22 receptors. Promotes self-renewal of mouse and human ESC due to β-catenin and c-Myc protein level stabilization. Commonly used in multiple stages of organoid generation.
The product is subject to the following: Abcam Restricted Use Statement
Abcam WAY-100635 maleate, 5-HT1A receptor antagonist, 50MG
MW 538.6 Da, Purity >98%. Potent, selective, silent 5-HT1A receptor antagonist (IC50 = 1.35 nM). Displays >100-fold selectivity for 5-HT1Arelative to a range of other CNS receptors including other 5-HT subtypes, adrenoceptors, dopamine, GABA, histamine and ion channels. Binds selectively to rodent brain 5-HT1A receptors *in vivo* (iv admin). Unlike WAY100135, WAY100635 displays no partial agonist activity in the ventral hippocampus of rats.
The product is subject to the following: Abcam Restricted Use Statement
Abcam A 769662, AMP-activated protein kinase activator, 10MG
MW 360.4 Da, Purity >99%. Potent, reversible activator of AMP-activated protein kinase (AMPK) (EC₅₀ = 0.8 μM). Directly activates native rat AMPK by mimicking the effects of AMP - it activates AMPK both allosterically and by inhibiting dephosphorylation of AMPK. Shown to inhibit Na+-K+-ATPase at higher concentrations (IC₅₀ = 57 μM) . Inhibits differentiation of adipocytes.
The product is subject to the following: Abcam Restricted Use Statement
Abcam x E-991 dihydrochloride, KCNQ channel blocker; blocks M current, 50MG
MW 449.4 Da, Purity >99%. Potent and selective blocker of KCNQ voltage-gated potassium channels. Blocks M current. (IC₅₀ values are 0.98 μM (M-current), 0.71 μM (KCNQ 2), 0.75 μM (KCNQX 1), >100 μM (Kv1.2) and >43 μM (Kv4.3). Potent pulmonary vasoconstrictor. Cognitive enhancer following oral administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Organic Chemistry Copper(II) phthalocyanine | 200MG | 147-14-8 | MFCD00010719
Copper(II) phthalocyanine, 200MG
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Storage: room temp
EINECS Number: 205-685-1
Sigma Organic Chemistry Copper(II) phthalocyanine | 2G | 147-14-8 | MFCD00010719
Copper(II) phthalocyanine, 2G
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Storage: room temp
EINECS Number: 205-685-1
Med Vet International Cyanocobalamin Injection, 1000mcg, 30ml, Vitamin B12
Cyanocobalamin is a man-made form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis. Cyanocobalamin is used to treat vitamin B12 deficiency with pernicious anemia and other conditions.
Sigma Organic Chemistry Vanadyl phthalocyanine | 500MG | 13930-88-6 | MFCD00041966
Vanadyl phthalocyanine, 500MG
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Storage: room temp
EINECS Number: 237-700-2
FRONTIER SPECIALTY CHEMICALS INC PROTOPORPHYRIN IX 8-13-B 250MG
NC2876535 PROTOPORPHYRIN IX 8-13-B 250MG
Sigma Organic Chemistry Silicon phthalocyanine dichloride | 1G | 19333-10-9 | MFCD00010723
Silicon phthalocyanine dichloride, 1G
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Storage: room temp
EINECS Number: 242-969-4
Sigma Organic Chemistry 1,4,8,11,15,18,22,25-Octabutoxy-29H,31H-phthalocyanine | 1G | 116453-73-7 | MFCD00134589
1,4,8,11,15,18,22,25-Octabutoxy-29H,31H-phthalocyanine, 1G
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Linear Formula: C64H82N8O8
Storage: room temp
Apexbio Technology LLC TIN PROTOPORPHYRIN IX 2CL 50MG
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways